Medical Education and Awareness Content
Mechanism of Action of Viagra (Sildenafil)
Viagra | Sildenafil | Tadalafil | Cialis | Avanafil | Verdanafil | Levitra
PDE5 inhibitors like Sildenafil relax blood vessels, increasing penile blood flow and helping achieve/maintain erections. They block phosphodiesterase type 5 (PDE5), an enzyme that breaks down cyclic guanosine monophosphate (cGMP), a mediator of smooth muscle relaxation.
Reference:
- US FDA: "Sildenafil Citrate Tablets" (Rev. 2022)
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